Meibomian gland dysfunction
Conditions
Interventions
new meibomian gland massage device test group:meibomian gland massage
new meibomian gland massage device blank control group:use eye drops
meibomian gland massage forceps test group:meibomian gland massage
meibomian gland massage forceps blank control group:use eye drops
Sponsors
Eye Hospital, Wenzhou Medical University
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1.age >=16 years old; 2.diagnosis of moderate to severe obstructive meibomian gland dysfunction.
Exclusion criteria
Exclusion criteria: 1.loss of meibomian glands>2/3; 2.abnormal eyelid structure; 3.active ocular inflammation or other eye diseases such as glaucoma and punctale occlusion; 4.history of ocular surgery or trauma; 5.wearing contact lenses within the past 2 weeks; 6.receiving relevant physical therapy or intense pulsed light therapy within the past 6 months; 7.long-term ocular medications; 8.autoimmune disease requiring systemic treatment; 9.pregnant or lactating women.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| the degree of blockage of the meibomian gland openings;the meibum quality;the meibum expressibility; | — |
Secondary
| Measure | Time frame |
|---|---|
| scores of OSDI;scores of SPEED;tear meniscus height;non-invasive tear break-up time;lipid layer thickness;Fluorescein-stained tear film break-up time;corneal ?uorescein staining;Eyelid margin;loss of meibomian glands; | — |
Countries
China
Contacts
Public ContactZelin Zhao
Eye Hospital, Wenzhou Medical University
Outcome results
None listed