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Correlation analysis of adverse reactions of cytarabine syndrome caused by cytarabine in children with acute lymphoblastic leukemia

Correlation analysis of adverse reactions of cytarabine syndrome caused by cytarabine in children with acute lymphoblastic leukemia

Status
Recruiting
Phases
Phase 4
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500098713
Enrollment
Unknown
Registered
2025-03-12
Start date
2025-01-22
Completion date
Unknown
Last updated
2025-03-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute lymphoblastic leukemia

Interventions

Normal temperature group (observation group) and the fever group (control group):none

Sponsors

Shenzhen Children’s Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
No minimum to 18 Years

Inclusion criteria

Inclusion criteria: 1.The child was diagnosed with acute lymphoblastic leukemia; 2.The treatment plan and risk grouping criteria were based on CCCG-AlL-2020 Childhood acute lymphoblastic leukemia treatmentprotocol; 3.Their age ranged from 1 month to 18 years; 4.All patients were newly diagnosed; 5.The body temperature was normal prior to chemotherapy. 6.The patient demonstrates excellent compliance, meaning they are capable of completing the stipulated treatment protocol and cooperating with relevant examinations and follow-ups.

Exclusion criteria

Exclusion criteria: 1.Mature B-ALL, mixed leukemia; 2.Combined with other tumors; 3.Combined with autoimmune diseases; 4.Children with incomplete diagnosis and treatment data;

Design outcomes

Primary

MeasureTime frame
White blood cell(WBC);Neutrophil (NEU);Hypersensitive C-reactive protein;Interleukin- 6;Procalcitonin;

Secondary

MeasureTime frame
Total bilirubin;Aspartate aminotransferase;Alanine aminotransferase;Total Protein;Creatinine;Urea;

Countries

China

Contacts

Public ContactXuejuan Li

Shenzhen Children’s Hospital

xuejuanli@126.com+86 755 83008256

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026