None listed
Conditions
Interventions
R-T group:Take test sample A in the first cycle and test sample B in the second cycle
Test sample A is one of liposome vitamin C and regular vitamin C, and test sample B is the other of liposome vitamin C and regular vitamin C.
T-R group:Take test sample B in the first cycle and test sample A in the second cycle
Sponsors
the First People's Hospital of Kunshan
Eligibility
Sex/Gender
Male
Age
18 Years to 55 Years
Inclusion criteria
Inclusion criteria: 1. Male aged 18-55 years (including borderline values); 2. Body mass index (BMI) 19.0 Kg/m2 – 28.0 Kg/m2 (including borderline values); 3. No history of allergy or intolerance to vitamin C; 4. Signed informed consent form.
Exclusion criteria
Exclusion criteria: 1. Patients with serious diseases of the heart, liver, kidney and hematopoietic system, and mental illness; 2. Patients with hypoglycemia; 3. Patients who need to take medication during the trial; 4. Patients with special dietary habits: vegetarians, ketogenic dieters (high fat, low carbohydrates), etc.; 5. Patients who plan to donate blood during the trial; 6. Patients who have suffered from major clinically significant diseases or major surgical operations within 3 months before screening, or patients who plan to undergo surgery during the study; 7. Alcoholics or patients who cannot abstain from alcohol during the trial; 8. Smokers or patients who cannot abstain from smoking during the trial; 9. Patients who cannot eat or have difficulty swallowing; 10. Patients who have used any medication (including prescription drugs, over-the-counter drugs, Chinese medicine, health products, etc.) within 2 weeks before screening; 11. Patients who cannot tolerate intravenous puncture or have a history of blood or needle phobia; 12. Patients with lactose intolerance; 13. Patients with a history of drug abuse or drug use; 14. Those with a history of malignant tumors in the past 5 years; 15. Those who have received vaccines in the past 90 days; 16. Those who are considered by the researchers to have poor compliance, or the researchers believe that the subjects have any other conditions that make them unsuitable for participation in this trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| C-max;AUC(0-t);AUC(0-8); | — |
Secondary
| Measure | Time frame |
|---|---|
| T-max;t1/2; | — |
Countries
China
Contacts
Public ContactChen Yafang
the First People's Hospital of Kunshan
Outcome results
None listed