Atelectasis
Conditions
Interventions
Group A FiO2=30%:FiO2=30%,Lung recruitment
Group B FiO2=40%:FiO2=40% ,Lung recruitment
Group C FiO2=60%:FiO2=60% Lung recruitment
Group D FiO2=80%: FiO2=80%Lung recruitment
Sponsors
Subei People's Hospital of Jiangsu province
Eligibility
Sex/Gender
All
Age
18 Years to 64 Years
Inclusion criteria
Inclusion criteria: 1.ASA: I ~ II; 2.voluntarily participating in this study by signing an informed consent form; 3.scheduled for elective laparotomy under general anesthesia; 4.no gender restrictions, aged 18 to 64 years, with a BMI of 18 to 25 kg/m^2; 5.expected surgical duration of >=1.5 hours, and intraoperative blood loss <=500 ml.
Exclusion criteria
Exclusion criteria: 1.History of thoracic surgery Chest X-ray or CT scan indicating pneumothorax or pulmonary bullae; 2. Lung diseases: chronic bronchitis, asthma, moderate to severe obstructive ventilatory dysfunction Preoperative pulse oxygen saturation (SpO2) < 90% in room air or SpO2 < 95% under oxygen supplementation Contraindications for lung recruitment: elevated intracranial pressure, hypovolemic shock, right heart failure Severe heart disease (New York Heart Association, NYHA Class III or IV; acute coronary syndrome or persistent ventricular tachyarrhythmia) Participation in other interventional studies or refusal to enroll.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Lung compliance response time; | — |
Secondary
| Measure | Time frame |
|---|---|
| Hypoxemia;Oxygenation index;Atelectasis;Pulmonary complications; | — |
Countries
China
Contacts
Public ContactJu Gao
Subei People's Hospital of Jiangsu province
Outcome results
None listed