None
Conditions
Interventions
Group H+A (alfentanil + cyclopropofol group):The first young female patient was given alfentanil 10ug/kg, waited 5 minutes, and then received an initial predose of cyclopropofol (0.4mg/kg) within 1 mi
Group H (cyclopropofol group):The same dose of 5 ml normal saline was given. Five minutes later, cyclopropofol (0.4mg/kg) was given as a bolus, diluted to 30 ml, and the subsequent dose of the latter
Sponsors
Hangzhou Obstetrics and Gynecology Hospital
Eligibility
Sex/Gender
Female
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1. Age > = 18 years old female. 2. Surgery under general anesthesia is required. 3. ASA (American Society of Anesthesiologists) Class I-II. 4. Body mass index (BMI) 18-30 kg/m². 5. Sign the informed consent form, be able to accept the experimental method, and voluntarily be the subject of the subject.
Exclusion criteria
Exclusion criteria: 1. Age> 65 years old. 2. Allergy to cyclopofol or contraindications to the use of cyclopofol (soybean allergy). 3. Preoperative consciousness impairment or chronic pain, long-term use of analgesics and psychiatric drugs (including opioids, NSAIDs, sedatives, antidepressants). 4. Predicted difficult airway or history of abnormal anesthesia. 5. Patients with tumors, severe cardiovascular and cerebrovascular diseases, etc. 6. Use of sedatives, antiemetics, anti-itching drugs 24 hours before surgery, or monoamine oxidase inhibitory drugs or antidepressants within 15 days. 7. Those who do not agree to participate or are participating in other drug trial researchers.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The lowest bispectral index (BIS) was recorded within 5 min after the end of cyclopropofol infusion.; | — |
Secondary
| Measure | Time frame |
|---|---|
| Sedation within 5 min after the end of the cyclopropofol infusion; | — |
Countries
China
Contacts
Public ContactQiu Xiaoxiao
Hangzhou Obstetrics and Gynecology Hospital
Outcome results
None listed