Early Gastric Cancer
Conditions
Interventions
Gold Standard:Histopathological diagnosis: All target lesions were biopsied or resected, and histopathological diagnosis was performed. The diagnostic procedure is evaluated by an experienced patholog
Index test:The study was designed to enroll 764 lesions suspected of being abnormal as identified by white light endoscopy. Patients with lesions observed using ME-NBI were randomly assigned in a 1:1
Sponsors
Zhejiang Cancer Hospital
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1.Patients with suspected lesions detected by conventional white light endoscopy requiring further endoscopic narrow-band imaging evaluation; 2. Age >=18 years old, gender is not limited; 3. ECOG score 0 or 1; 4. No previous tumor-related history; 5. Gastroscopy and pathological examination can be performed within 7 days after signing the informed consent; 6. Subject and family members are able to understand the study protocol and are willing to participate in the study, providing written informed consent.
Exclusion criteria
Exclusion criteria: 1. Patients who have previously undergone ESD/ partial gastrectomy; 2. A history of other neoplastic diseases, or other genetic diseases; 3. Patients with serious medical diseases, such as grade III or above cardiac dysfunction (NYHA criteria), ischemic heart disease, heart infarction, or angina pectoris, or heart infarction 6 months before screening, poorly controlled diabetes, poorly controlled hypertension, and echocardiographic ejection fraction 6mg/L; 6. The subject or family member is unable to understand the conditions and objectives of the study; 7. Accurate ME-NBI assessment cannot be performed on lesions and ulcers/erosions that are partially or completely obscured by excessive bleeding or mucus.
Design outcomes
Secondary
| Measure | Time frame |
|---|---|
| The positive predicative value;The negative predicative value; | — |
Primary
| Measure | Time frame |
|---|---|
| The diagnostic sensitivity;The diagnostic specificity; | — |
Countries
China
Contacts
Public ContactShi Wang
Zhejiang Cancer Hospital
Outcome results
None listed