Acute kidney injury
Conditions
Interventions
Control group (Group C, conventional perfusion strategy):conventional perfusion strategy.Conventional extracorporeal circulation perfusion method was used i.e., pump flow was adjusted according to bod
Test group (group D, oxygen delivery-guided perfusion strategy):oxygen delivery-guided perfusion strategy.The oxygen supply index (DO2i) was used as a parameter to guide the perfusion flow, and DO2i w
Sponsors
Yongchuan Hospital of Chongqing Medical University
Eligibility
Sex/Gender
All
Age
20 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Patients undergoing elective surgery who are going to undergo cardiac surgery. 2. Age>=20 years old and <=75 years old. 3. American Society of Anesthesiology (ASA) grade II.~IV. 4. New York Heart Association (NYHA) grade II or IV.
Exclusion criteria
Exclusion criteria: 1. Patients with severe renal insufficiency before surgery, end-stage renal disease receiving renal replacement therapy, and patients receiving nephrotoxic drug therapy. 2. Patients undergoing rare or complex cardiac surgery (left heart mass resection, aortic arch reconstruction, etc.), patients with hypothermic arrest surgery. 3. Patients with signs or symptoms of septic shock before surgery. 4. Patients with moderate and severe anemia, which is very likely to affect postoperative AKI. 5. Patients who refuse to participate in the program by themselves or their family members.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| serum creatinine(SCr);Incidence of AKI; | — |
Secondary
| Measure | Time frame |
|---|---|
| red blood cell infusion rate and volume;Length of stay in the ICU;length of hospital stay;Post-operative mortality;postoperative complication(e.g. peritoneal dialysis, re-operation, re-tracheal intubation, lung infection); | — |
Countries
China
Contacts
Public ContactNa Zhang
Yongchuan Hospital of Chongqing Medical University
Outcome results
None listed