Histiocytic neoplasm
Conditions
Interventions
Observation group:None
Sponsors
Department of Pathology, West China Hospital, Sichuan University
Eligibility
Sex/Gender
All
Age
No minimum to 90 Years
Inclusion criteria
Inclusion criteria: The submitted specimen is from an intracranial lesion, or from a non-intracranial lesion with radiological evidence of intracranial involvement. Histologically, tumor cells exhibit a diffuse proliferation of mature, histiocytic-like cells. The histiocytes are positive for CD68 and CD163, but negative for CD1a and Langerin.
Exclusion criteria
Exclusion criteria: The submitted specimen does not belong to an intracranial lesion and there is no evidence of intracranial involvement. Histologically, there is a proliferation of histiocytes, but it is not diffuse and the tumor cells do not exhibit uniform morphology. The histiocytes are positive for CD1a and Langerin.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Morphological features of intracranial histiocytic neoplasams;Cyclin D1 immunohistochemical staining;BRAF V600E mutation;ALK fusion;Location of the lesion;Histopathological type of histiocytic neoplasms;Survival time; | — |
Secondary
| Measure | Time frame |
|---|---|
| Age;Sex;Comorbidities;History of malignant tumors;Postoperative complications;Total length of hospital stay after surgery; | — |
Countries
China
Contacts
Public ContactWenyan Zhang
Department of Pathology, West China Hospital, Sichuan University
Outcome results
None listed