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A Comparative study by various techniques to expose intersegmental plane in the treatment of early peripheral lung cancer through minimally invasive segmental resection

A Comparative study by various techniques to expose intersegmental plane in the treatment of early peripheral lung cancer through minimally invasive segmental resection

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500098637
Enrollment
Unknown
Registered
2025-03-11
Start date
2024-04-29
Completion date
Unknown
Last updated
2025-03-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Peripheral lung cancer in stage Ia

Interventions

Control group:Combined intravenous and inhalation general anesthesia was used with double-lumen endotracheal intubation, single lung ventilation on the unaffected side, and collapsed lung on the affec
After 15-20 minutes, the anesthesiologist was instructed to fully puff up the lungs, ventilate the lungs on the unaffected side, and observe that the lung segment on the affected side is completely at

Sponsors

Army Medical Center of PLA
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1.Subjects voluntarily will participate this study and provide an informed consent form. 2.The participants are 18 to 65 years old. 3.Both FEV1 and DLCO are greater than 80% of the predicted values. 4.The diameter of the tumor to be resected is<=2 cm. Preoperative CT scans indicate that GGO is located in the target lung segment, aligning with the NCCN guidelines for pulmonary segment surgery.

Exclusion criteria

Exclusion criteria: 1.Subjects had a history of allergy to contrast media. 2.Subjects are on anticoagulant medication prior to surgery. 3.The patient presented with severe thoracic adhesions. 4.Preoperative computed tomography (CT) identified the tumor at the junction of lung segments, raising the possibility of missing the lesion during segmentectomy. 5.The patient cannot tolerate surgery due to the severe comorbidities. 6.Given the patient's severe condition and history of significant cardiovascular and cerebrovascular diseases, surgical intervention will be deemed intolerable.

Design outcomes

Primary

MeasureTime frame
The distance difference between the modified inflation- deflation method, the pulmonary artery watershed drainage method and the fluorescence method in different lung segments was compared.;

Secondary

MeasureTime frame
Time for the formation of intersegmental plane by modified inflation-deflation method or pulmonary artery watershed drainage;The success rate of modified inflation- deflation method or pulmonary artery watershed drainage method to determine the intersegmental planes will be documented.;Intraoperative blood loss;Perioperative complication rate;Segmental resection rate;Extended resection rate;Drainage volume;Duration of chest tube drainage;Hospital stay;Treatment cost;

Countries

China

Contacts

Public ContactYonggeng Feng/Bo Deng

Army Medical Center of PLA

finger0412@126.com+86 18523920270

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026