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Based on biomechanical methods to explore the effect of knee osteoarthritis complicated with sarcopenia on knee joint stability

Based on biomechanical methods to explore the effect of knee osteoarthritis complicated with sarcopenia on knee joint stability

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500098635
Enrollment
Unknown
Registered
2025-03-11
Start date
2025-03-11
Completion date
Unknown
Last updated
2025-03-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Sacorpenia

Interventions

Sarcopenia group:None
Knee osteoarthritis complicated with sarcopenia group:None
Healthy people group:None

Sponsors

Guangdong Provincial Hospital of Traditional Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
50 Years to 70 Years

Inclusion criteria

Inclusion criteria: Inclusion Criteria for the Experimental Group: Patients with simple sarcopenia: (1) Age 50-70 years old; (2) Those who meet the 2019 criteria for sarcopenia by the Asian Sarcopenia Working Group (AWGS) are: male grip strength =12s; (3) voluntarily join this trial and sign the informed consent form; (4) Those with good compliance. Patients with simple knee osteoarthritis (1) Age 50-70 years old; (2) meet the diagnostic criteria of the American Rheumatology Association KOA, and the Kellgren-Lawrence stage is less than stage IV; (3) Patients with unilateral knee osteoarthritis; (4) voluntarily join this trial and sign the informed consent form; (5) Those with good compliance. Patients with sarcopenia and knee osteoarthritis: (1) Age 50-70 years old; (2) Those who meet the 2019 judgment criteria for sarcopenia by the Asian Sarcopenia Working Group (AWGS): male grip strength =12s; (3) Meet the diagnostic criteria of the American Rheumatology Association KOA, and the Kellgren-Lawrence stage is less than stage IV; (4) Patients with unilateral knee osteoarthritis; (5) Voluntarily join this trial and sign the informed consent form; (6) Those with good compliance. Inclusion Criteria for the Control Group: (1) Age 50-70 years old; (2) Those who are in good health, have no neuroskeletal muscular system diseases or symptoms, and have no other systemic diseases, such as respiratory system, circulatory system, etc.; (3) No history of major trauma or surgery of the lower limbs; (4) does not meet the criteria for sarcopenia; (5) voluntarily join this trial and sign the informed consent form; (6) Those with good compliance.

Exclusion criteria

Exclusion criteria: 1. Severe cardiovascular and cerebrovascular diseases, nervous system diseases; 2. Patients with recent fractures or surgeries; 3. There are implanted items in the body (including but not limited to pacemakers, artificial joints, steel plates, etc.); 4. Patients with severe osteoporosis, mental illness and cognitive impairment.

Design outcomes

Primary

MeasureTime frame
Kinematic stability;Joint laxity;

Secondary

MeasureTime frame
Thickness of quadriceps;Thickness of hamstring ;Electromyography;

Countries

China

Contacts

Public ContactZeng Xiaolong

Guangdong Provincial Hospital of Traditional Chinese Medicine

1962238666@qq.com+86 20 8188 7233

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026