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Effects of Transcranial Alternating Current Stimulation on Upper Limb Motor Function After Stroke: A Randomized Controlled Trial

Effects of Transcranial Alternating Current Stimulation on Upper Limb Motor Function After Stroke: A Randomized Controlled Clinical Trial

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500098629
Enrollment
Unknown
Registered
2025-03-11
Start date
2025-04-15
Completion date
Unknown
Last updated
2025-10-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Stroke

Interventions

Sponsors

Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
45 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Diagnosed ischemic/hemorrhagic stroke by CT/MRI; 2. Age >=45 years old and =3 months and 20 points; Secondary school education and above> 24 points; 6. Unilateral upper limb motor dysfunction, Brunnstrom stage > = stage II; 7. Right-handed; 8. Participate voluntarily and sign the form of inform.

Exclusion criteria

Exclusion criteria: 1.Individuals with unstable vital signs in the acute phase; 2.Those with aphasia, hearing impairment, or other conditions that hinder normal verbal communication; 3.Individuals with severe bone, joint, or muscle diseases; 4.Pregnant or breastfeeding women; 5.Individuals with severe organ diseases or serious mental disorders, including but not limited to the following conditions: Cardiac diseases (e.g., myocardial infarction, atrial fibrillation) Liver diseases (e.g., liver failure, liver cancer) Kidney diseases (e.g., end-stage renal disease) Pulmonary diseases (e.g., respiratory failure) Mental disorders (e.g., schizophrenia) 6.Individuals with contraindications for transcranial alternating current stimulation (tACS) and electroencephalography (EEG), such as cardiac pacemakers, cardiac stents, claustrophobia, cranial trauma or skull defects, scalp infections, or wounds; 7.Individuals with a history of epilepsy; 8.Participation in another clinical trial project within one month prior to enrollment or currently participating in another study.

Design outcomes

Primary

MeasureTime frame
Fugl-Meyer assessment of the upper extremity, FMA-UE Score;

Secondary

MeasureTime frame
Action Research Arm;National Institutes of Health Stroke , NIHSS Score;Modified Barthel index, MBI;Stroke-Specific Quality of Life ;Grip strength and pinch strength;Traditional Chinese Medicine syndrome score;EEG indicators;Magnetic resonance spectroscopy;MRI indicators;

Countries

China

Contacts

Public ContactXue Xin

Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine

xuexin@shutcm.edu.cn+86 152 0215 1580

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026