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The effects of different sedative hypnotics on the EEG of patients: An EEG study

Effects of different sedative and hypnotic drugs on adult brain resting-stimulation interactions: an EEG study

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500098617
Enrollment
Unknown
Registered
2025-03-11
Start date
2017-01-02
Completion date
Unknown
Last updated
2025-03-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients requiring surgical procedures

Interventions

propofol group:Propofol was injected for induction and EEG data from induction to recovery were recorded
dexmedetomidine :Dexmedetomidine was injected for induction and EEG data from induction to recovery were recorded
ketemine:Ketemine was injected for induction and EEG data from induction to recovery were recorded

Sponsors

Huashan Hospital affiliated to Fudan University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: Patients aged 18 to 60 years old, of either gender, with a BMI of 18 to 25 kg/m², right-handed, with an ASA grade I, scheduled for general anesthesia, Mallampati grade I-II, and who understand and sign the informed consent form.

Exclusion criteria

Exclusion criteria: History of smoking and alcohol abuse, history of anesthesia surgery, psycho-neurological disorders, drug dependence, history of taking any drugs within 2 weeks, hearing impairment, cardiovascular disease, expectation of difficult airway, drug (including history of allergic reaction or contraindication to any of the three anesthetics in this trial) or food allergy, pregnant and lactating patients, participants in other clinical trials in the last 3 months.

Design outcomes

Primary

MeasureTime frame
EEG;

Countries

China

Contacts

Public ContactZhang Jun

Fudan University Shanghai Cancer Center

snapzhang@aliyun.com+86 138 1715 3025

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026