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The effect of dexmedetomidine nasal spray on sleep quality and pain improvement in patients with postherpetic neuralgia

The effect of dexmedetomidine nasal spray on sleep quality and pain improvement in patients with postherpetic neuralgia

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500098608
Enrollment
Unknown
Registered
2025-03-11
Start date
2025-04-30
Completion date
Unknown
Last updated
2025-03-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Herpes zoster neuralgia

Interventions

Dexmedetomidine group:Dexmedetomidine nasal drops 100 µ g ((50ug per nostril)) were given preoperatively, and the operation was performed after the drug took effect
Normal saline group:Patients in the dexmedetomidine group were given the same amount of normal saline before surgery and then underwent surgery

Sponsors

The First Affiliated Hospital of Wannan Medical College
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. Be between the ages of 18-75; 2. Diagnosed with herpetic neuralgia with a course of 1-6 months; 3. Pain persistent or intermittent onset, VAS score >=4 points; 4. Sign the informed consent form.

Exclusion criteria

Exclusion criteria: 1. Allergy to dexmedetomidine; 2. Severe heart, liver and kidney insufficiency; 3. Being receiving other treatments that may affect sleep or pain; 4. Have a history of mental illness or cognitive impairment.

Design outcomes

Primary

MeasureTime frame
Pittsburgh sleep quality index (PSQI);Visual analogue scale (VAS);Incidence of adverse drug reactions;

Secondary

MeasureTime frame
Perioperative vital signs;

Countries

China

Contacts

Public ContactWen Huaichang

The First Affiliated Hospital of Wannan Medical College

wenhc19851207@163.com+86 136 9656 8215

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026