cervical incompetence
Conditions
Interventions
intervention group:cervical cerclage
Sponsors
Drum Tower Hospital
Eligibility
Sex/Gender
Female
Age
18 Years to 50 Years
Inclusion criteria
Inclusion criteria: 1. 16 to 25+6 weeks pregnant; 2. amniotic sac reaching or exceeding the external cervical os on vaginal examination; 3. no uterine contraction, intact membranes (both chorionic and amniotic membranes).
Exclusion criteria
Exclusion criteria: 1. premature rupture of membrane; 2. abdominal pain; 3. vaginal bleeding; 4. vaginal purulent discharge; 5. temperature >38?; 6. fetal heart rate >160bpm; 7. fetal demise; 8. fetal chromosomal abnormalities or fetal malformations; 9. WBC >15*10^9/L; 10. severe co-morbidities or obstetric complications;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Newborn survival without complications; | — |
Secondary
| Measure | Time frame |
|---|---|
| gestational age of delivery;chorioamnionitis;neonatal complications;cerclage surgery complications;time of cerclage removal;mode of delivery;co-morbidities and complications in pregnancy;use of dexamethasone;use of MgSO4;indications for cesarean section or assisted vaginal delivery;postpartum complications;intra-amniotic inflammation;intra-amniotic infection;Inflammatory markers in maternal blood;maternal vaginal microbiota testing; | — |
Countries
China
Contacts
Public ContactGu Ning
Drum Tower Hospital
Outcome results
None listed