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Development and transformation of multi-dimensional molecular imaging probes driven by key biological information in tumor radiotherapy

Development and transformation of multi-dimensional molecular imaging probes driven by key biological information in tumor radiotherapy

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500098579
Enrollment
Unknown
Registered
2025-03-11
Start date
2025-03-18
Completion date
Unknown
Last updated
2025-03-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Lung cancer

Interventions

Study group: patients with clinically confirmed or highly suspected malignancy:Targeted tumor microenvironment molecular probe imaging.
Healthy control group:Targeted tumor microenvironment molecular probe imaging.

Sponsors

Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1.Adult patients (aged 18 or above), regardless of gender; 2.Patients with nasopharyngeal cancer, esophageal cancer, and lung cancer diagnosed clinically and pathologically, who have not received any treatment; And agree to undergo histopathological examination (if not performed before imaging); Healthy volunteers; 3.Willing and able to follow schedule visits, treatment plans, laboratory tests, and other related procedures; 4.Agree to probe imaging of key biomarkers for tumor radiotherapy and 18F-FDG PET imaging.

Exclusion criteria

Exclusion criteria: 1.Acute systemic diseases and electrolyte imbalances; 2.Pregnant or lactating women planning to become pregnant within six months; 3.The patient or their legal representative is unable or unwilling to sign the informed consent form.

Design outcomes

Primary

MeasureTime frame
Standardized uptake values of region of interest;

Secondary

MeasureTime frame
Pathological diagnosis of tumor tissue;Radioactivity in the blood and urine samples;

Countries

China

Contacts

Public ContactXiaoli Lan

Union Hospital, Tongji Medical College, Huazhong University of Science and Technology

hzslxl@163.com+86 27 85726685

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026