Helicobacter pylori infection
Conditions
Interventions
Cases group:None
Sponsors
Southern Medical University Shenzhen Hospital
Eligibility
Sex/Gender
All
Age
6 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Voluntarily sign the informed consent form, demonstrate compliance with the protocol, and be capable of undergoing the required procedures; 2. Aged between 6 and 75 years (inclusive), regardless of gender; 3. Helicobacter pylori infection confirmed by urea breath test (UBT), scheduled to undergo gastroscopy, and no history of any antibiotic treatment in the past month; 4. Cohabiting family member(s) with Helicobacter pylori infection confirmed by UBT and also scheduled to undergo gastroscopy.
Exclusion criteria
Exclusion criteria: 1. Have systemic diseases involving other organs, including severe diseases of important organs such as the heart, lungs, kidneys, immune-mediated disorders, metabolic diseases (e.g., diabetes, thyroid disorders), or malignant tumors. 2. Tested positive for antibodies against hepatitis C virus (HCV), human immunodeficiency virus (HIV), or syphilis during the screening period. 3. Significant laboratory abnormalities, as determined by the investigator, that may compromise patient safety or prevent completion of the clinical study: 1) Renal function: creatinine >1.5 times the upper limit of normal (ULN);2) Chronic liver disease and/or liver dysfunction: defined as AST >=1.5 times the upper limit of normal (ULN), and/or ALT >= 1.5 times the ULN, and/or total bilirubin >= 1.5 times the ULN. 4. Have other psychiatric disorders, excluding depression or anxiety disorders. 5. Have a history of substance abuse or alcohol abuse. 6. Pregnant or breastfeeding women. 7. Have severe psychological or behavioral issues that prevent cooperation with the study process or may interfere with the study. 8. Have participated in any clinical trial within the 3 months prior to signing the informed consent form. 9. The investigator deems the participant unsuitable for inclusion in this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Genomics of Helicobacter pylori; | — |
Secondary
| Measure | Time frame |
|---|---|
| Antimicrobial resistance of Helicobacter pylori;Treatment of Helicobacter pylori infection; | — |
Countries
China
Contacts
Public ContactYe Chen
Southern Medical University Shenzhen Hospital
Outcome results
None listed