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To evaluate the effect of different levels of PEEP ventilation on atelectasis in elderly patients after laparoscopic ambulatory surgery based on LUS score

To evaluate the effect of different levels of PEEP ventilation on atelectasis in elderly patients after laparoscopic ambulatory surgery based on LUS score

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500098563
Enrollment
Unknown
Registered
2025-03-11
Start date
2024-08-27
Completion date
Unknown
Last updated
2025-03-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

pulmonary atelectasis

Interventions

?group:Positive end-expiratory pressure ventilation PEEP=5cm H20
? group:Positive end-expiratory pressure ventilation PEEP=8cm H20
? group:Positive end-expiratory pressure ventilation PEEP=10cm H20

Sponsors

Shanghai Jiading Central Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
65 Years to 85 Years

Inclusion criteria

Inclusion criteria: 1. Age >= 65 years old; 2. American ASA anesthesia Score grade I or II; 3. Preoperative chest radiograph or CT was normal,aparoscopic inguinal hernia repair under endotracheal intubation, aspiration and anesthesia.

Exclusion criteria

Exclusion criteria: 1. Postoperative VAS pain score of 4 or more; 2. Patients with respiratory diseases, such as COPD, chronic branch, asthma, pulmonary bulla, preoperative upper respiratory tract infection, cardiopulmonary insufficiency and other serious disease; 3. Emergency surgery; 4. Height 30 kg/m^2; 5. Patients with intraoperative hemodynamic instability; 6. Patients with preoperative anemia (hemoglobin <100 g/L); 7. Have a history of chest surgery.

Design outcomes

Primary

MeasureTime frame
Lung ultrasound score;

Secondary

MeasureTime frame
Respiratory mechanical index: peak airway pressure, plateau airway pressure;Hemodynamic index: heart rate, mean arterial pressure;Blood oxygen saturation;Numerical Pain Score (NRS);Immunological indicators: interleukin IL-1 ß IL-16IL-6 Tumor necrosis factor TNF - a;

Countries

China

Contacts

Public ContactWang Kai

Shanghai Jiading Central Hospital

victorwaaa@163.com+86 21 67073174

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026