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Difference in efficacy of tissue rotation after liposuction versus areolar incision for glandular tissue removal in the treatment of Gynecomastia

Difference in efficacy of tissue rotation after liposuction versus areolar incision for glandular tissue removal in the treatment of Gynecomastia : a multicentre, prospective, randomized controlled clinical study

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500098552
Enrollment
Unknown
Registered
2025-03-10
Start date
2025-03-10
Completion date
Unknown
Last updated
2025-03-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Gynecomastia

Interventions

B:Liposuction combined with areola incision group:Liposuction is combined with a small areolar incision to remove residual glandular connective tissue
A:Liposuction combined with tissue rotation:Liposuction combined with tissue rotation group

Sponsors

Xi'an Jiaotong University Second Affiliated Hospital
Lead Sponsor

Eligibility

Sex/Gender
Male
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: 1. Between 18-60 years old; 2. Simon scale of gynecomastia: Simon I or II; 3. Preoperative breast palpation, color ultrasound, and magnetic resonance (MRI) examination reports are all GYN; 4. The course of the disease is more than 12 months, and there is no sign of spontaneous regression; 5. Determined to be glandular fat type according to breast MRI examination (glandular volume accounts for 25%-75% of the total breast volume); 6. There is no abnormality in the development of the vulva genitals, and the sex hormone test is normal; 7. Voluntarily join the clinical study, randomly select one of the two surgical methods of tissue atherectomy after liposuction or areolar small incision excision of residual glands after liposuction for treatment, and the postoperative resources will be subject to follow-up observation scheduled by the clinical study, and they will be informed about this study and sign the informed consent form.

Exclusion criteria

Exclusion criteria: 1. Inoperable with severe heart, liver, kidney and blood system diseases; 2. Patients with preoperative breast examination or impact science showing the presence of other lesions in the breast except for gynecomastia, such as suspicious nodules in the breast, suspicious calcification of the breast or malignant in the pathological examination of postoperative specimens; 3. Drug-induced gynecomastia: abnormal breast development caused by chronic hepatitis, liver cirrhosis or long-term use of isoniazid, estrogen, androgen suppression drugs, diuretics, etc.; 4. Pathological gynecomastia: breast development caused by pituitary tumors, hypogonadism, pseudohermaphroditism, etc.; 5. Gynecomastia with a course of less than 1 year and can be treated with medication; 6. Patients who are unwilling to accept the randomization of this study to select the surgical regimen and cannot return to the clinic on time.

Design outcomes

Primary

MeasureTime frame
BREAST-Q questionnaire survey;Investigator Satisfaction (VAS scale);Patient Satisfaction (VAS scale);

Countries

China

Contacts

Public ContactLiang Baobao

Xi'an Jiaotong University Second Affiliated Hospital

xuebaoc@mail.xjtu.edu.cn+86 29 8767 9512

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026