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Causal Temporal Network Early Warning of Cardiac Surgery Associated-Acute Kidney Injury (REACT-01)

Causal Temporal Network Early Warning of acute kidney injury after cardiac surgery (REACT-01) : a single-center prospective randomized controlled clinical trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500098538
Enrollment
Unknown
Registered
2025-03-10
Start date
2025-03-10
Completion date
Unknown
Last updated
2025-03-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cardiac Surgery Associated-Acute Kidney Injury, defined according to KDIGO guidelines

Interventions

Traditional treatment group (control group):none
REACT Model Prediction Group (Experimental group):Use REACT model to predict AKI occurrence time

Sponsors

Drum Tower Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1.underwent open cardiac surgery; 2.Age >=18 years; 3.No previous history of renal insufficiency, nephritis, kidney transplantation or dialysis treatment; 4.Sign informed consent;

Exclusion criteria

Exclusion criteria: 1.History of malignancy affects life expectancy; 2.Renal insufficiency was confirmed by preoperative renal function examination; 3.Gestational state; 4.Subjects are required to withdraw from the study at any time; 5.Circumstances that the researcher considers to be affecting the conclusion of the experiment should be excluded;

Design outcomes

Primary

MeasureTime frame
Incidence of AKI 7 days after surgery;

Secondary

MeasureTime frame
The incidence of AKI in different stages 7 days after surgery;Serum creatinine value at discharge;All-cause mortality at 30, 60, and 90 days after surgery;Length of stay in ICU, total length of stay;Whether to use renal replacement therapy (RRT), and how long to use RRT therapy;Eligible for Major Adverse Kidney Event (MAKE);

Countries

China

Contacts

Public ContactChen chen

Drum Tower Hospital

njchencheng@163.com+86 25 83106666

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026