Infection of H.pylori
Conditions
Interventions
Experimental group:Vonoprazan-Minocycline dual therapy
Sponsors
Army Medical Center of PLA
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1.Adults aged 18 to 60, male or female; 2.Positive result of urea breath test; 3.No previous H.pylori eradication;
Exclusion criteria
Exclusion criteria: 1.PPIs, potassium competitive acid blockers, antibiotics, H2 receptor antagonists, bismuth agents, probiotics, P-CABs and other drugs were used within four weeks before treatment; 2.Patients with allergies to the drugs used in this study; 3.History of acute gastroenteritis within 4 weeks prior to treatment; 4.Pregnant/lactating women, or patients with birth plans during study period; 5.Patients with previous gastric or intestinal surgery; 6.Patients with severe comorbidities or malignancies; 7.Patients with liver disease; 8.No agree to signing informed consent form;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Eradication rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| Patients' compliance;Incidence of adverse reactions;Impact to gut microbiota;Recurrence rate;Economic benefit; | — |
Countries
China
Contacts
Public ContactLan Chunhui
Army Medical Center of PLA
Outcome results
None listed