orthopaedics
Conditions
Interventions
Rimazolam group:None
Cyclopofol group:None
Sponsors
First Affiliated Hospital of Guangxi Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 90 Years
Inclusion criteria
Inclusion criteria: Patients with American Association of Anesthesiologists (American Society of Anesthesiologists, ASA) Grade I or grade, physical mass Index (body mass index, BMI) 18-25 kg/m² and elective general anesthesia
Exclusion criteria
Exclusion criteria: Patients with allergy to Remazolam or with a previous and family history of severe allergy, patients with hemodynamic instability, arrhythmia, patients with craniocerebral injury or intracranial hypertension, and patients with severe cardiac, pulmonary, hepatic, and renal abnormalities. The exclusion criteria were severe postoperative fever, infection, bleeding, and unplanned transfer to intensive care units.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Stop the medication until the time of recovery;Time of drug withdrawal to extubation;Time for withdrawal to time to leave the recovery room; length of stay; | — |
Secondary
| Measure | Time frame |
|---|---|
| Preoperative and postoperative liver and kidney function;Blood glucose values after and during 1 hour;Use of postoperative analgesic agents;Hemodynamic changes during the perioperative period;Postoperative analgesic medication use;Operation time;Intraoperative fluid replacement volume;Amount of bleeding;Urine output;Intraoperative analgesic drug dose;Intraoperative anesthetic drug dose;Intraoperative vasoactive drug dose;Number of intraoperative episodes of hypotension;Dose of analgesic drugs used in the recovery room;Incidence of adverse reactions in the recovery chamber;Duration of anesthesia; | — |
Countries
China
Contacts
Public ContactZhong Yu
The First Affiliated Hospital of Guangxi Medical University
Outcome results
None listed