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Prospective cohort study on risk factors for osteoporosis in patients with knee osteoarthritis undergoing joint arthroplasty

Prospective cohort study on risk factors for osteoporosis in patients with knee osteoarthritis undergoing joint arthroplasty

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500098529
Enrollment
Unknown
Registered
2025-03-10
Start date
2025-03-12
Completion date
Unknown
Last updated
2025-03-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Knee Osteoarthritis, osteoporosis

Interventions

Case series:None

Sponsors

The First Affiliated Hospital of Soochow University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
55 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Age>=55 years old; 2. After March 1, 2025, patients who are mainly diagnosed with knee osteoarthritis and are hospitalized for the first unilateral total knee arthroplasty or unicompartmental replacement; 3. Preoperative examination to rule out contraindications to surgery; 4. Have not participated in other clinical research projects in the past 4 weeks; 5. Able to be fully informed and sign the informed consent form.

Exclusion criteria

Exclusion criteria: 1. Patients undergoing knee arthroplasty for joint disorders other than knee osteoarthritis, those requiring bilateral knee arthroplasty, or revision knee arthroplasty patients; 2.Presence of surgical contraindications identified during preoperative evaluations; 3.Participation in other clinical research studies within the past 4 weeks; 4.Subjects deemed unsuitable for inclusion by the investigator.

Design outcomes

Primary

MeasureTime frame
Preoperative bone mineral density test results;

Secondary

MeasureTime frame
Bone metabolism index test results;Demographic characteristics;Sleep status self-rating scale scores were recorded;Thrombosis Risk Factor Assessment Form score;Modified Apfel postoperative malante vomiting (PONV) prevention and management assessment form score;VAS score;HSS score of the knee joint;Time to KOA diagnosis;Preoperative x-rays;

Countries

China

Contacts

Public ContactJun Zhou

The First Affiliated Hospital of Soochow University

royf1@163.com+86 135 8486 0109

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026