Postoperative recovery quality
Conditions
Interventions
Dexmetomidine combined with oxelidine group:Dexmedetomidine 0.5µg/ (kg·h) was pumped before induction for 10min, and oxelidine 1mg was given 30min before the end of surgery
Oxelidine group:Pump the same dose of normal saline for 10min before anesthesia induction,and Oxelidine 1mg was given 30min before the end of surgery
Dexmetomidine group:Dexmedetomidine 0.5µg/ (kg·h) was pumped before induction for 10min,and the same dose of normal saline was given 30min before the end of surgery
Normal saline group:Given the same dose of normal saline
Sponsors
The Affiliated Hospital of Xuzhou Medical University
Eligibility
Sex/Gender
All
Age
25 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Patients undergoing thyroidectomy under elective general anesthesia; 2. Preoperative American Society of Anesthesiologists grade I ~ II; 3. Aged 25-65 years old; 4. Agree to participate in the study and sign the informed consent.
Exclusion criteria
Exclusion criteria: 1. Cough, hoarseness and sore throat before operation; 2. Preoperative bradycardia or atrioventricular block; 3. Operation time 3h; 4. Long-term use of opioids; 5. History of thyroid surgery; 6. Complicated with pregnancy, mental disorders, respiratory depression, severe heart, brain and lung diseases, liver and kidney failure; 7. Known or suspected gastrointestinal obstruction; 8. Other contraindications of surgery or anesthesia; 9. Inclusion of other interventional studies.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Postoperative recovery quality score; | — |
Secondary
| Measure | Time frame |
|---|---|
| Postoperative recovery quality score;Incidence of sore throat 24 hours after surgery;pain score;The incidence of bradycardia, hypotension, arrhythmia and PACU hypoxemia during operation;;Postoperative recovery time of spontaneous respiration, recovery time, extubation time, PACU resident time;Fatigue score;Postoperative adverse reactions (fever, bradycardia, tachycardia, hypertension, hypotension, dizziness, respiratory depression, dry mouth, nausea, vomiting, pain, etc.).;Length of postoperative hospital stay; | — |
Countries
China
Contacts
Public ContactQin Yin
The Affiliated Hospital of Xuzhou Medical University
Outcome results
None listed