Acute Kidney Injury
Conditions
Interventions
Control Group (Contrast Agent Group):Invasive coronary evaluation/intervention with low-dose contrast media under intravascular ultrasound guidance
Experimental Group (Zero Contrast Agent Group):Invasive coronary evaluation/intervention guided by intravascular ultrasound and coronary flow reserve fraction.
Sponsors
The Second Affiliated Hospital of Army Medical University
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1 Age >= 18 years; 2 Baseline eGFR between 15 and 59 ml/min/1.73 m^2; 3 Scheduled for elective invasive coronary evaluation/intervention; 4 Availability of coronary angiography imaging data within the past six months; 5 Willing to participate in this study and sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1 Patients with end-stage renal disease requiring dialysis; 2 Use of iodinated contrast media within 7 days before the procedure; 3 Allergy to contrast media; 4 Previous coronary imaging showing complex anatomical lesions such as extremely angulated or tortuous target lesions, severe calcification with bifurcation, left main stem ostial lesions, chronic total occlusion (CTO), etc.; 5 Pregnancy; (6) Presence of mental illness or other reasons that prevent cooperation or poor compliance.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Renal Function;Incidence of postoperative acute kidney injury; | — |
Countries
China
Contacts
Public ContactXiaohui Zhao
The Second Affiliated Hospital of Army Medical University
Outcome results
None listed