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The Correlation Between Hypoxic Burden Characteristics and Cardiovascular Disease Risk in Obese Patients with Obstructive Sleep Apnea

The Correlation Between Hypoxic Burden Characteristics and Cardiovascular Disease Risk in Obese Patients with Obstructive Sleep Apnea

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500098511
Enrollment
Unknown
Registered
2025-03-10
Start date
2025-03-15
Completion date
Unknown
Last updated
2025-03-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cardiovascular Disease

Interventions

Observation Group:None

Sponsors

West China Hospital of Sichuan University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: Age: 18-60 years old; OSA group: AHI>=15 times/hour, BMI=15 times/hour, BMI>=28kg/m^2, obese group: AHI=28kg/m^2Healthy control group: AHI<5 times/hour, BMI<24kg/m^2.

Exclusion criteria

Exclusion criteria: 1.A history of diabetes and currently on medication or insulin therapy; 2. Poorly controlled cardiovascular diseases; 3. Chronic pulmonary diseases or chronic hypercapnia; 4. Pre-existing OSA or previous OSA treatment prior to enrollment; 5. Obese patients with a history of or currently undergoing related treatment; 6. Patients with total sleep time < 4 hours or poor-quality PSG monitoring, and those unable to complete the questionnaire survey.

Design outcomes

Primary

MeasureTime frame
Cardiovascular disease risk;—

Secondary

MeasureTime frame
Cardiovascular mortality;—

Countries

China

Contacts

Public ContactGong Shu

West China Hospital of Sichuan University

gdy-29@163.com+86 189 8060 1417

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026