Alzheimers disease
Conditions
Interventions
mild AD:Transcranial photobiomodulation (tPBM) therapy and sham treatment regimens are for the patient/family caregiver to use a device to provide the patient with 10 minutes of phototherapy once dail
NC:Transcranial photobiomodulation (tPBM) therapy and sham treatment regimens are for the patient/family caregiver to use a device to provide the patient with 10 minutes of phototherapy once daily dur
MCI-AD:Transcranial photobiomodulation (tPBM) therapy and sham treatment regimens are for the patient/family caregiver to use a device to provide the patient with 10 minutes of phototherapy once daily
Moderate AD:Transcranial photobiomodulation (tPBM) therapy and sham treatment regimens are for the patient/family caregiver to use a device to provide the patient with 10 minutes of phototherapy once
Cognitively normal:Sham treatment
mild AD:Sham treatment
MCI-AD:Sham treatment
Moderate AD:Sham treatment
Sponsors
Hainan General Hospital
Eligibility
Sex/Gender
All
Age
55 Years to 90 Years
Inclusion criteria
Inclusion criteria: 1. Age ranges from 55-90; 2. Patients with normal cognition, diagnosed with MCI-AD, mild or moderate AD dementia; 3. Physical examination results conducted within the past 6 months show that the patient is in good health.
Exclusion criteria
Exclusion criteria: 1. History of stroke; 2. Patients with depression; 3. Systemic diseases that may cause cognitive impairment; 4. Inability to complete neuropsychological tests or contraindications for MRI.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Brain volume;Neuropsychological Tests;Aß-SUVR;DCE perfusion;DTI-ALPS index; | — |
Countries
China
Contacts
Public ContactFeng Chen
Hainan General Hospital
Outcome results
None listed