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A risk-predicted nomogram for sepsis-induced organ dysfunction in adult critically ill patients based on clinical parameters

Development and Validation of a Nomogram for Predicting Organ Dysfunction in Sepsis: A Risk Factor Analysis Based on Logistic Regression

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500098500
Enrollment
Unknown
Registered
2025-03-10
Start date
2024-11-01
Completion date
Unknown
Last updated
2025-03-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Organ dysfunction caused by sepsis: Sepsis-associated coagulopathy, Sepsis-associated Acute Respiratory Distress Syndrome (ARDS), Sepsis-associated hepatic injury.

Interventions

Gold Standard:The Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3)
Index test:Clinical data were collected at the time of sepsis diagnosis, including vital signs (temperature, respiratory rate, heart rate, blood pressure) and comprehensive laboratory parameters. Labo

Sponsors

First People's Hospital of Huzhou
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1.Documented or clinically suspected infection; 2.Acute organ dysfunction manifested by an increase in Sequential Organ Failure Assessment (SOFA) score of 2 points or more from baseline;

Exclusion criteria

Exclusion criteria: 1.Age 20% missing); 8.Lost to follow-up;

Design outcomes

Primary

MeasureTime frame
Complete blood count;Neutrophil count value;Lymphocyte count;

Secondary

MeasureTime frame
vital signs;

Countries

China

Contacts

Public ContactLi Zhong

First People's Hospital of Huzhou

51103@zjhu.edu.cn+86 137 5706 1864

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026