Skip to content

Clinical effects study of autogenous pulp transplantation in mature permanent teeth with chronic apical periodontitis

Clinical effects study of autogenous pulp transplantation in mature permanent teeth with chronic apical periodontitis

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500098486
Enrollment
Unknown
Registered
2025-03-10
Start date
2025-03-11
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

chronic apical periodontitis

Interventions

Test group:Autogenous pulp transplantation
Control group:Root canal treatment

Sponsors

The Affiliated Stomatological Hospital of Nanjing Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 50 Years

Inclusion criteria

Inclusion criteria: 1. Chronic periapical periodontitis was diagnosed in the anterior teeth or premolars; 2. Age >= 18 years old and no history of systemic diseases affecting oral treatment; 3. The third molar with vertical impacted should be removed without endodontic and periodontal disease ; 4. The affected tooth can be completely removed during the extraction process without damaging the pulp tissue; 5. Normal opening and good fit; 6. Fully understand the purpose, process, risks and benefits of the test, agree to join the test and sign the informed consent.

Exclusion criteria

Exclusion criteria: 1. The affected tooth has no preservation value, and the remaining tooth tissue has no repair value; 2. The root curvature of the affected tooth is relatively large; 3. The affected tooth had a periodontal pocket =3mm; 4. Contraindications for tooth extraction; 5. Other patients deemed unsuitable for participation in this trial by the investigator.

Design outcomes

Primary

MeasureTime frame
Treatment success rate;

Secondary

MeasureTime frame
Pulp electrical viability test;Size of root tip shadow of periapical film;

Countries

China

Contacts

Public ContactLi Jin

The Affiliated Stomatological Hospital of Nanjing Medical University

lijin6806@163.com+86 138 1588 8120

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Aug 10, 2026