Type 2 Diabetic Diabetic Kidney Disease
Conditions
Interventions
People with type 2 diabetic nephropathy and orthostatic hypotension:None
Type 2 diabetic nephropathy without orthostatic hypotension group:None
Sponsors
Beijing Pinggu District Hospital
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Type 2 diabetic nephropathy combined with orthostatic hypotension group: (1) Meets the diagnostic criteria for type 2 diabetic nephropathy as defined in the 2021 Chinese Guidelines for the Prevention and Treatment of Diabetic Nephropathy. (2) Within 3 minutes after changing from the supine position to the standing position, systolic blood pressure drops by more than 20 mmHg and/or diastolic blood pressure drops by more than 10 mmHg. (3) Age >= 18 years. (4) Agrees to participate in this study. 2. Type 2 diabetic nephropathy without orthostatic hypotension group: (1) Meets the diagnostic criteria for type 2 diabetic nephropathy as defined in the 2021 Chinese Guidelines for the Prevention and Treatment of Diabetic Nephropathy. (2) Within 3 minutes after changing from the supine position to the standing position, systolic blood pressure drops by less than 20 mmHg and/or diastolic blood pressure drops by less than 10 mmHg. (3) Age >= 18 years. (4) Agrees to participate in this study.
Exclusion criteria
Exclusion criteria: 1. During hospitalization, the ambulatory blood pressure measurement was not completed. 2. Undergoing renal replacement therapy. 3. Primary central nervous system injury or secondary central nervous system injury (Parkinson's disease, spinal cord injury, brainstem injury, etc.). 4. Patients with a history of mental illness, abnormal thyroid function, and long-term alcohol consumption. 5. Patients with liver function grade B or C. 6. Patients with cardiac function grade III or IV, and severe arrhythmia. 7. Patients with long-term nutritional disorders or severe chronic diseases. 8. Patients in the acute bleeding or acute infection stage. 9. Pregnant or patients with advanced cancer.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Orthostatic Hypotension;glycosylated hemoglobin; | — |
Secondary
| Measure | Time frame |
|---|---|
| Urinary protein creatinine ratio;Serum albumin level;glomerular filtration rate;Complications of diabetes; | — |
Countries
China
Contacts
Public ContactYan Guo
Beijing Pinggu Hospital
Outcome results
None listed