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Multi-sequence magnetic resonance imaging radiomics predicts the epidermal growth factor receptor mutation status in patients with non-small cell lung cancer brain metastases

Multi-sequence magnetic resonance imaging radiomics predicts the epidermal growth factor receptor mutation status in patients with non-small cell lung cancer brain metastases

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500098475
Enrollment
Unknown
Registered
2025-03-10
Start date
2024-11-01
Completion date
Unknown
Last updated
2025-03-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

2C25.0 Bronchial or lung adenocarcinoma

Interventions

Training group:None
Validation group:None

Sponsors

Second Xiangya Hospital of CSU
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1.Patients with non-small cell lung cancer confirmed by pathological tissue biopsy specimens; Not receiving any treatment prior to admission; 2.Brain metastases before initial treatment, chest CT, brain MRI, and EGFR genetic testing were performed; No history of other malignancies.

Exclusion criteria

Exclusion criteria: 1.Incomplete image scanning or poor image quality (including low signal-to-noise ratio, low contrast, image artifacts, image distortion); 2.The boundaries of the primary lesion or brain metastases are unclear and cannot be accurately delineated; Has a history of other malignancies.

Design outcomes

Primary

MeasureTime frame
area under receiver operating curve, AUC-ROC;—

Countries

China

Contacts

Public ContactZifeng Ding

Second Xiangya Hospital of CSU

dzf299@163.com+86 731 85295729

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026