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Effect of different glucose-lowering regimens on serum endotrophin levels in patients with newly diagnosed type 2 diabetes

Effect of different glucose-lowering regimens on serum endotrophin levels in patients with newly diagnosed type 2 diabetes mellitus

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500098470
Enrollment
Unknown
Registered
2025-03-10
Start date
2025-03-12
Completion date
Unknown
Last updated
2025-03-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Type 2 diabetes mellitus

Interventions

Initial Continuous Insulin Pump Group:none
Four subcutaneous insulin injections (insulin glargine + NovoMix) group:none
Oral metformin group:none
Healthy control group:none

Sponsors

Huai'an Second People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Type 2 diabetes population: 1. type 2 diabetes mellitus (1999 WHO diagnostic criteria); 2. 18 <= age <= 65 years. Healthy population: 1. 18 <= age <= 65 years; 2. fasting blood glucose < 7. 0 mmol/L, random blood glucose < 11. 1mmol/L.

Exclusion criteria

Exclusion criteria: 1. Other types of diabetes; 2. use of any type of antidiabetic drugs before admission; 3. diabetes acute metabolic disorder, such as diabetic ketoacidosis, non-ketotic hyperosmolar coma, etc.; 4. Any type of infection; 5. has comorbidities such as gravity, liver, kidney and cerebrovascular diseases; 6. any malignant disease; 7. surgical or other stress conditions.

Design outcomes

Primary

MeasureTime frame
Endotrophin;

Secondary

MeasureTime frame
fasting plasma glucose;glycated hemoglobin;triacylglycerol;total cholesterol;low-density lipoprotein cholesterol;high-density lipoprotein cholesterol;fasting insulin;fasting C-peptide;

Countries

China

Contacts

Public ContactFeng Bai

Huai'an Second People's Hospital

jiefu6887579@163.com+86 134 2018 2598

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026