Cervical cancer
Conditions
Interventions
Sponsors
Zhujiang Hospital of Southern Medical University
Eligibility
Sex/Gender
Female
Age
18 Years to 50 Years
Inclusion criteria
Inclusion criteria: 1.Aged 18-50 years old, with a history of sexual activity; 2. HPV and TCT tests are performed concurrently in the gynecology clinic; 3. Those with abnormal HPV and TCT test results undergo tissue pathological testing;
Exclusion criteria
Exclusion criteria: 1.Pregnant or breastfeeding; 2.Patients with immunological disorders or severe autoimmune diseases, such as AIDS, SLE; 3.Those who have had organ transplants or are currently using immunosuppressive agents; 4.Use of vaginal douching within 48 hours before sample collection; 5. Use of vaginal probiotics within one month before sample collection; 6. Use of vaginal antibiotics or antifungal treatments within one month before sample collection; 7.History of surgery related to cervical intraepithelial neoplasia (CIN), including but not limited to conization of the cervix, LEEP procedures, etc. 8. Blood samples (avoid sampling during menstruation), insufficient remaining sample volume to support subsequent analysis needs, and samples not stored as required.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| PCR validation of DNA methylation sites associated with cervical cance;Multi-target DNA methylation detection; | — |
Secondary
| Measure | Time frame |
|---|---|
| STDs pathogens DNA test;HPV E6/E7 Testing;Metagenomic Sequencing; | — |
Countries
China
Contacts
Public ContactMuxuan Chen
Zhujiang Hospital of Southern Medical University
Outcome results
None listed