Symptomatic intracranial atherosclerotic stenosis
Conditions
Interventions
symptomatic ICAS group:None
Sponsors
The first affiliated hostipal of nanchang university
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1.Patients with symptomatic ICAS diagnosed by clinical and imaging (intracranial artery stenosis>50%, and Responsible artery stenosis leading to TIA or ischemic stroke) Or large artery stenosis>70%); 2.18-75 years old; 3.Sign the informed consent form; 4. Able to complete HR-VWI and ASL multi-modal scanning package sequences.
Exclusion criteria
Exclusion criteria: 1.History of head and neck vascular surgery within the past 3 months; 2.Patients with an unknown cause of stroke or potential cardiogenic stroke (e.g., atrial fibrillation); 3.Known sick sinus syndrome, severe sinus bradycardia (50 BPM), second degree or more severe atrioventricular block; 4.Unable to complete or refuse baseline and follow-up MRI scans; 5. MRI head movement and poor image; 6. Patients with lack of major clinical function assessment and biochemical indicators.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| acute ischemic stroke; | — |
Secondary
| Measure | Time frame |
|---|---|
| The follow-up time was more than 2 years or death;acute cerebral hemorrhage; | — |
Countries
China
Contacts
Public ContactXianjun Zeng
The first affiliated hostipal of nanchang university
Outcome results
None listed