Chronic Kidney Disease Patients with Periodontitis
Conditions
Interventions
control group (oral hygiene instruction):NA
intervention group (non-surgical periodontal therapy):NA
Sponsors
Shanghai Ninth People's Hospital, Shanghai JiaoTong University School of Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 18-75 years old; 1.Generalized II-IV stage periodontitis; 2.Stage 1-5 chronic kidney disease;
Exclusion criteria
Exclusion criteria: 1.Patients with malignancy; 2.Limited life expectancy (less than 2 years); 3.There are systemic diseases that affect the performance/effectiveness of periodontal treatment; 4.Patients with bleeding disorders or coagulation disorders who cannot receive non-surgical periodontal treatment; 5.Women who are pregnant or planning to become pregnant during the study period; 6.Patients who require prophylactic use of antibiotics before dental treatment; 7.Received antibiotic treatment within the past 3 months; 8.Received periodontal treatment within the past 12 months (Excluding Supragingival Scaling); 9.Currently participating in other clinical trials;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| eGFR; | — |
Secondary
| Measure | Time frame |
|---|---|
| Number of lost teeth;probing depth;Clinical attachment level;plaque index;Tooth Mobility;Full mouth bleeding index;electrocardiogram;chest CT;Blood creatinine Blood uric acid, endogenous creatinine clearance rate, total protein, albumin, prealbumin, C-reactive protein, serum iron, ferritin, transferrin saturation, blood;blood urea nitrogen;Blood uric acid;endogenous creatinine clearance rate;total protein;albumin;prealbumin;C-reactive protein;serum iron;ferritin;blood electrolytes;blood calcium;blood phosphorus;blood parathyroid hormone;active vitamin D;transferrin saturation; | — |
Countries
China
Contacts
Public ContactChen Huiwen
Shanghai Ninth People's Hospital, Shanghai JiaoTong University School of Medicine
Outcome results
None listed