Gastric cancer
Conditions
Interventions
High chronic stress level group:None
Low chronic stress level group:None
Sponsors
Southern Medical University Southern Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1.Sign the informed consent form voluntarily; 2.Sex is not limited, 18<= age <=75 years old; 3.According to the 15th edition of the Japan Statute of gastric cancer in 2017, the primary lesion of the stomach was diagnosed by endoscopic biopsy; 4.According to the judgment of the treating physician, patients with gastric adenocarcinoma should be treated with immune checkpoint inhibitor before radical gastrectomy.
Exclusion criteria
Exclusion criteria: 1.Pregnant or lactating women; 2.Severe mental illness; 3.History of upper abdominal surgery (except laparoscopic cholecystectomy); 4.Patients with gastric cancer who were not willing to undergo neoadjuvant immunotherapy; 5.History of sustained systemic corticosteroid therapy in the past 1 month; 6.Patients with active infection, active or refractory autoimmune disease, or uncontrolled systemic disease; 7.According to the judgment of the researcher, it is not suitable to participate in this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Chronic stress;Tumor Regression Grade; | — |
Secondary
| Measure | Time frame |
|---|---|
| Quality of Life;ACTH;Plasma adrenaline;Serum cortisol;Norepinephrine; | — |
Countries
China
Contacts
Public ContactXinhua Chen
Southern Medical University Southern Hospital
Outcome results
None listed