emergence agitation
Conditions
Interventions
esmketamine group ( group S):Group S received intravenous injection of esmketamine 0. 3 mg / kg
control group ( group C):group C was injected with equal volume of normal saline intravenously
Sponsors
The First Affiliated Hospital of Zhengzhou University
Eligibility
Sex/Gender
All
Age
3 Years to 10 Years
Inclusion criteria
Inclusion criteria: (1) the American Society of Anesthesiologist (ASA) Physical Status classifcation ?-? (2) children aged 3–10 years,weighing between 10 and 50 kg
Exclusion criteria
Exclusion criteria: (1) Allergy to related anesthetic drugs (2) History of acute upper respiratory tract infection within 14 days prior to surgery. (3) Severe organic lesions of vital organs such as heart, liver, and kidney (4) Presence of psychiatric and neurological diseases that hindered cooperation (5) History of premature birth ,congenital, hereditary, psychiatric or epilepsy disorders (6) History of anaesthesia or sedation recently (7) Severe preoperative anxiety of parents
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Postoperative behavioral change score;pain score;The paediatric anaesthesia emergence delirium (PAED) scores; | — |
Secondary
| Measure | Time frame |
|---|---|
| Vital signs at the time of extubation;Vital signs when exiting the resuscitation room;extubation time;PACU residence time;Length of hospital stay;the number of additional cases of propofol in recovery period,;the number of additional cases of analgesics in recovery period;The occurrence of adverse events in recovery period; | — |
Countries
China
Contacts
Public ContactXiang-yun Feng
The First Affiliated Hospital of Zhengzhou University
Outcome results
None listed