Lung cancer
Conditions
Interventions
Usual care group (GroupC):The management goals of group C were MAP > 65mmHg (adjusted to no more than ±20% fluctuation before anesthesia for hypertensive patients), urine output > 0.5ml/kg/h, lactate
P[v-a]CO2 group (group P):The goal of group P management is to infuse HES 250ml (if PPV>13) or norepinephrine 0.01~0.1µg/kg/min (if PPV75% and P[v-a]CO2>6mmHg). If SCvO2 95% and Hb is suitable, P[v-a]
Sponsors
The First Affiliated Hospital of Dalian Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 100 Years
Inclusion criteria
Inclusion criteria: Patients undergoing elective thoracoscopic lobectomy Age >= 18 years old ASA Grading I.~III Voluntarily signed informed consent
Exclusion criteria
Exclusion criteria: Abnormal preoperative lung function (FEV1= 13 points; Patients with renal insufficiency (serum creatinine and urea nitrogen more than 1.2 times the normal range) or abnormal liver function, AST/ALT greater than 1/5/2 times the normal value; maximum vital capacity (FVC) 30kg/m^2 Allergy to hydroxyethyl starch History of upper respiratory tract or pulmonary infection within the past 4 weeks Severe pleural effusion and atelectasis before surgery Patient refuses to participate in the study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Postoperative recovery quality; | — |
Countries
China
Contacts
Public ContactSun Defeng
The First Affiliated Hospital of Dalian Medical University
Outcome results
None listed