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Post-Transplant Alterations in the Intestinal Microbiota and the Incidence of Transplant-Associated Complications: A Prospective Observational Investigation

Post-Transplant Alterations in the Intestinal Microbiota and the Incidence of Transplant-Associated Complications: A Prospective Observational Investigation

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500098399
Enrollment
Unknown
Registered
2025-03-07
Start date
2025-04-01
Completion date
Unknown
Last updated
2025-03-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Graft Versus Host Disease

Interventions

Hematopoietic stem cell transplantation group:None

Sponsors

The Second Affiliated Hospital of Army Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
No minimum to 65 Years

Inclusion criteria

Inclusion criteria: (1) From December 2024 to December 2027, patients undergoing allogeneic hematopoietic stem cell transplantation at this center who are <=65 years old; (2) Patients who have resided in the Southwest region (Chongqing, Sichuan, Guizhou, Yunnan) for the past three years; (3) Patients who voluntarily participate in this study and sign an informed consent form.

Exclusion criteria

Exclusion criteria: (1) Exclude patients with inflammatory bowel disease, irritable bowel syndrome, or gastrointestinal malignant tumors; (2) Exclude patients with infectious diseases such as HIV, syphilis; (3) Exclude patients with a history of intestinal surgery; (4) Exclude pregnant and lactating women; (5) Exclude any other situations that the researcher deems unsuitable for inclusion in the study.

Design outcomes

Primary

MeasureTime frame
Incidence of acute gastrointestinal graft-versus-host disease;

Secondary

MeasureTime frame
Incidence of chronic gastrointestinal graft-versus-host disease;Incidence of Implantation failure and poor implantation;Gastrointestinal Infection rate;

Countries

China

Contacts

Public ContactXi Zhang

The Second Affiliated Hospital of Army Medical University

zhangxxi@sina.com+86 138 0831 0064

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026