quality of postoperative recovery
Conditions
Interventions
Esketamine group:Esketamine
Sponsors
General Hospital of the Eastern Theatre of the Chinese People's Liberation Army
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. ASA classification ? - ? or ? 2. Age 18-65 years old 3. Elective thoracoscopic pulmonary resection (thoracoscopic pulmonary wedge resection, lobectomy, segmental resection)
Exclusion criteria
Exclusion criteria: 1. Refusal to participate 2. Known allergy or hypersensitivity to study drugs (esketamine, ropivacaine) 3. contraindication to erector spinae plane block, e.g. coagulation disorders, abnormal puncture anatomy, puncture site infection, etc. 4. contraindication to esketamine, such as long-term poorly controlled hypertension, unstable ischaemic heart disease, increased intracranial pressure or intraocular pressure. 5. Severe hepatic dysfunction (Child-Pugh class C, D). 6. Renal failure (requiring renal replacement therapy) 7. Long-term use of analgesics (regular use > 4 weeks prior to the study at doses equal to or greater than 30 mg of oral morphine per day) 8. History of drug or alcohol abuse 9. Speech and language impairment and cognitive impairment 10. BMI >30 kg/m2 or <15 kg/m^2 11. Pregnant or lactating women
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 15-item Quality of Recovery score ; | — |
Secondary
| Measure | Time frame |
|---|---|
| NRS pain score at rest;NRS pain score during coughing;Asens Insomnia Scale Score;Hospital Anxiety and Depression Scale Score; | — |
Countries
China
Contacts
Public ContactLidong Zhang
General Hospital of the Eastern Theatre of the Chinese People's Liberation Army
Outcome results
None listed