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The effect of opioid free anesthesia on postoperative delirium in elderly patients undergoing prostate resection

The effect of opioid free anesthesia on postoperative delirium in elderly patients undergoing prostate resection

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500098392
Enrollment
Unknown
Registered
2025-03-07
Start date
2025-03-07
Completion date
Unknown
Last updated
2025-03-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Delirium

Interventions

Non opioid anesthesia group:Induction and intraoperative maintenance of general anesthesia mainly using ketamine combined with dexmedetomidine
Conventional opioid anesthesia group:Induction and intraoperative maintenance of general anesthesia with conventional opioid drugs sufentanil and remifentanil

Sponsors

Tianjin Medical University Second Hospital
Lead Sponsor

Eligibility

Sex/Gender
Male
Age
65 Years to 85 Years

Inclusion criteria

Inclusion criteria: 1. Patients undergoing elective prostate resection under general anesthesia 2. Age 65~85 years old 3. The estimated operation time < 2 h 4.BMI18~25(kg/m^2)

Exclusion criteria

Exclusion criteria: 1. Serious diseases of heart, liver, kidneys, lungs and other important organs. 2. Long-term use of analgesic and sedative drugs, anticoagulants or abuse of alcohol. 3. Allergies to anesthesia-related drugs, Parkinson's disease, epilepsy. 4. Preoperative Mini-Mental State Examination (MMSE) score < 24 points.

Design outcomes

Primary

MeasureTime frame
Incidence rate of delirium 3 days after operation;—

Secondary

MeasureTime frame
Postoperative Pain;Hypotension after anesthesia induction;—

Countries

China

Contacts

Public ContactNiu Tongxiang

Tianjin Medical University Second Hospital

13042205727@163.com+86 151 2260 8987

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026