Respiratory Tract Infections
Conditions
Interventions
Gold Standard:Pathogen culture method or PCR detection method
Index test:Utilize the CRISPR-based rapid nucleic acid detection method to screen for the following pathogens and antibiotic resistance genes: Influenza A virus, Influenza B virus, SARS-CoV-2 (COVID-1
Sponsors
Zhongshan Hospital, Fudan University
Eligibility
Sex/Gender
All
Age
18 Years to 95 Years
Inclusion criteria
Inclusion criteria: 1.Age between 18 and 95 years, gender not limited. 2.Suspected infected patients with respiratory symptoms or confirmed patients with untreated respiratory infections. 3.Retrospective sample collection uses previously remaining samples with the original informed consent; prospective sample collection is divided into two situations: First, additional collection of oropharyngeal swabs or sputum requires participants to sign a separate informed consent form; Second, the use of routine examination remaining samples, pleural effusion, or bronchoalveolar lavage fluid uses the general informed consent form signed upon hospital admission. 4.Patients can collect oropharyngeal swabs, sputum, bronchoalveolar lavage fluid, or pleural effusion samples. 5.Healthy volunteers: (1) Sign the informed consent form; (2) Age between 18 and 95 years, gender not limited; (3) Do not suffer from respiratory tract infections included in this study; (4) Do not have upper respiratory symptoms such as cough or rhinorrhea.
Exclusion criteria
Exclusion criteria: 1.Patients with incomplete medical records or untraceable sources. 2.The sample collection does not meet the research requirements. 3.Patients or healthy individuals outside the age range included in this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Sensitivity;Specificity;Overall Agreement Rate; | — |
Countries
China
Contacts
Public ContactJi Yuan
Zhongshan Hospital, Fudan University
Outcome results
None listed