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Metastatic lymph node burden and survival analysis head and neck squamous cell carcinoma in Shanghai Ninth Hospital: a single-center retrospective cohort study

Metastatic lymph node burden and survival analysis head and neck squamous cell carcinoma in Shanghai Ninth Hospital: a single-center retrospective cohort study

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500098365
Enrollment
Unknown
Registered
2025-03-06
Start date
2023-12-31
Completion date
Unknown
Last updated
2025-03-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Head and neck cancer, the seventh most common cancer globally, refers to malignant tumors originating in the lips, mouth, nasopharynx, oropharynx, hypopharynx, larynx, and salivary glands. Over 90% of head and neck cancers are squamous cell carcinomas. Smoking, excessive alcohol consumption, and HPV infection are recognized as the three major risk factors for head and neck squamous cell carcinoma.

Interventions

Cervical lymph node metastases group:None
No cervical lymph node metastases group:None

Sponsors

Shanghai Ninth People's Hospital, Shanghai JiaoTong University School of Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1.Patients with head and neck squamous cell carcinoma who were diagnosed and treated at Shanghai Ninth hospital from 2000 to 2023; 2.The pathological diagnosis of the tumor conforms to the WHO Histology Codes 8070-8076 and 8078; the tumor location conforms to the ICD-O-3 Topography Codes, including the oral cavity, oropharynx, larynx, hypopharynx, and other parts of the head and neck. 3.The clinical staging of the tumor conforms to the AJCC TNM staging system criteria or can be staged accordingly; 4.Patients received one or multiple treatments including surgery, radiotherapy, chemotherapy, or targeted therapy in our hospital; 5. Have complete and statistically available clinical inpatient records or diagnosis and treatment data.

Exclusion criteria

Exclusion criteria: 1.Patients without any inpatient treatment or unknown methods; 2.Squamous cell carcinoma originating from the nasopharynx; 3.Cases with missing patient information in the pathology system or hospital medical record system, as well as missing clinical or critical data;

Design outcomes

Primary

MeasureTime frame
Overall survival time;

Countries

China

Contacts

Public ContactYue He

Shanghai Ninth People's Hospital, Shanghai JiaoTong University School of Medicine

william5218@126.com+86 21 53072473

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026