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Neural mechanisms of impaired cognitive flexibility in schizophrenia: an ERP study from cue-switching tasks

Neural mechanisms of impaired cognitive flexibility in schizophrenia: an ERP study from cue-switching task

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500098355
Enrollment
Unknown
Registered
2025-03-06
Start date
2024-04-17
Completion date
Unknown
Last updated
2025-03-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

schizophrenia

Interventions

Schizophrenic group:None
Control group:None

Sponsors

Wuxi Mental Health Center
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. Meet the diagnostic criteria for schizophrenia in the Fifth edition of the Statistical Diagnostic Manual of Mental Disorders (DSM-5) of the American Psychiatric Association; 2.Age range 18-65 years old; 3.Single use of atypical antipsychotic drugs; 4.Education level is not less than junior high school (usually no less than 9 years of education); 5. Informed consent of guardian and cooperator

Exclusion criteria

Exclusion criteria: 1 meets the criteria for any other mental disorder in the DSM-5; 2 Patients with history of convulsive electroconvulsive therapy or modified electroconvulsive therapy within 6 months before enrollment; 3. Drugs that affect cognitive function, such as atropine and barbiturates, were used 2 weeks before enrollment; 4 Current or past neurological disease or any other serious physical disease that affects cognitive function; 5 History of organic brain diseases, seizures or head trauma; 6 Women of childbearing age during pregnancy and breastfeeding; 7 The visual acuity level cannot meet the requirements of the completed investigator.

Design outcomes

Primary

MeasureTime frame
event-related potentials P3;

Countries

China

Contacts

Public ContactZhouzhenhe

Wuxi Mental Health Center, Jiangsu Province, China

zhouzh@nimu.edu.cn+86 199 5630 3787

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026