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Clinical characteristics and risk factors of viral pneumonia combined with fungal infection based on metagenomic next-generation sequencing

Clinical characteristics and risk factors of viral pneumonia combined with fungal infection based on metagenomic next-generation sequencing

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500098354
Enrollment
Unknown
Registered
2025-03-06
Start date
2025-03-10
Completion date
Unknown
Last updated
2025-03-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

viral pneumonia combined with fungal infection

Interventions

Viral pneumonia without combined fungal Infections group:NA
Viral pneumonia combined with fungal infections group:NA

Sponsors

Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Respiratory symptoms such as fever, cough, sputum, and dyspnoea; 2. CT scan of the chest showed exudates, solid changes, infiltrates, and pleural effusions; 3. Patients consented to fibreoptic bronchoscopy and were sent for alveolar lavage fluid mNGS testing; 4. mNGS test results suggest viral positivity.

Exclusion criteria

Exclusion criteria: 1. Patients have a combination of trauma or severe infectious disease elsewhere; 2. Incomplete clinical data; 3. Patients are younger than 18 years old.

Design outcomes

Primary

MeasureTime frame
Proportion of viral pneumonia combined with fungal infections;—

Secondary

MeasureTime frame
The proportion of mNGS accurately diagnosing fungal infections;—

Countries

China

Contacts

Public ContactXiang Fei

Union Hospital, Tongji Medical College, Huazhong University of Science and Technology

93135729@qq.com+86 18971550171

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026