global developmental delay
Conditions
Interventions
Experimental group (true stimulation group):On the basis of conventional rehabilitation treatment, the experimental group of children will receive transcranial alternating current stimulation treatmen
Control group (sham stimulation group):Children in the control group will receive regular rehabilitation training and be given pseudo-stimulation therapy with the same frequency and duration, with the
Sponsors
The Third Affiliated Hospital of Zhengzhou University
Eligibility
Sex/Gender
All
Age
2 Years to 5 Years
Inclusion criteria
Inclusion criteria: (1) Age: 24 months ~60 months; (2) Meet the diagnostic criteria for global developmental delay in the DSM-5; (3) GESELL Development Scale assessment: two or more ability areas below 75 points, which must include adaptive performance district; (4) Parents or guardians agree to participate in the study, complete the pre-treatment examination, and sign the informed consent.
Exclusion criteria
Exclusion criteria: (1) Patients with limb movement disorders such as cerebral palsy and spinal cord injury; (2) Patients with severe hearing or visual impairment or other diseases affecting assessment; (3) Patients with epilepsy or other serious neurological diseases; (4) There is a clear cause of developmental delay, such as encephalitis after birth, brain trauma, cerebral hemorrhage, etc., or a clear diagnosis of heredity patients with metabolic diseases and neurodegenerative diseases; (5) Have a pacemaker or other electronic implant; (6) There are metal implants or intracranial metal fragments; (7) Recently received other brain stimulation treatment; (8) Allergic or contraindicated to electrical stimulation therapy.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Gesell Developmental Schedules; | — |
Secondary
| Measure | Time frame |
|---|---|
| Functional Near-Infrared Spectroscopy;Electroencephalogram;Normal Development of Social Skills from Infame to Junior High School Children(S-M) score;Child Behavior Checklist (CBCL);Clinical global Impression Improvement Scale (CGI-I);Parent observation scale; | — |
Countries
China
Contacts
Public ContactZhu Dengna
The Third Affiliated Hospital of Zhengzhou University
Outcome results
None listed