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Improvement of the multidimensional clinical database of sleep-disordered breathing based on a multicenter clinical cohort

Improvement of the multidimensional clinical database of sleep-disordered breathing based on a multicenter clinical cohort

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500098324
Enrollment
Unknown
Registered
2025-03-06
Start date
2025-03-15
Completion date
Unknown
Last updated
2025-03-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Obstructive sleep apnea (OSA), Central sleep apnea syndrome (CSAS), Other sleep breathing disorders (SBD)

Interventions

Case series:NA

Sponsors

Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Patients diagnosed with OSA, CSAS, or other forms of SBD; 2. Individuals with a history of attempted CPAP therapy but demonstrating poor adherence or suboptimal treatment outcomes; 3. Patients with comorbid chronic diseases, such as cardiovascular conditions (e.g., hypertension, coronary artery disease) and metabolic disorders (e.g., diabetes, obesity); 4. Individuals with a body mass index (BMI) below 32 kg/m^2 or 40 kg/m^2, meeting additional clinical indications.

Exclusion criteria

Exclusion criteria: 1. Patients with a body mass index (BMI) exceeding 40 kg/m² who also present with severe palatal airway obstruction; 2. Patients with anatomical abnormalities that significantly affect the airway structure, such as severe nasal septum deviation or tonsillar hypertrophy; 3. Patients with severe comorbidities that may impair respiratory function; 4. Patients who are allergic to the study equipment or materials, or those unable to ensure long-term follow-up adherence.

Design outcomes

Primary

MeasureTime frame
Establishment of a multi-center clinical cohort and database sample library for SBD patients;

Secondary

MeasureTime frame
Clinical characteristics, course evolution, and interaction with other chronic diseases of SBD patients;

Countries

China

Contacts

Public ContactNian Xiong

Union Hospital, Tongji Medical College, Huazhong University of Science and Technology

nianxiong@hust.edu.cn+86 27 85877677

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026