Alzheimers disease
Conditions
Interventions
Observation group:None
Sponsors
Shandong Provincial Hospital of Shandong First Medical University
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Age= 3 months or assessed by a specialist); Clinical decision-making is made based on the patient’s ability to safely participate in the treatment regimen; 7. Mental disease protocol: stable mental status (as assessed by the specialist); Clinical decision-making based on the patient’s ability to safely participate in the treatment regimen; 8. The subject is allowed to use cholinesterase inhibitors and memantine; 9. The subject is able to complete the cognitive ability test specified in the protocol; 10. The subject should be a stable and reliable caregiver, and the caregiver will help the subject participate in the whole study process. The caregiver must accompany the subject for study visits and must have sufficient interaction and communication with the subject to provide valuable information for study-related questionnaires and scale assessments; 11. Sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Bleeding disorders or taking anticoagulants. 2. Rule out acute or subacute bleeding, major bleeding, more than 4 microbleeds, cortical infarction (> 1.5 cm), more than 1 infarct (> 1.5 cm), surface siderosis, diffuse white matter disease. 3. Exclude non-Alzheimer's disease neurological degenerative disease. 4. Rule out angina, myocardial infarction, congestive heart failure. 5. Rule out other clinically significant systemic diseases, uncontrolled diabetes, uncontrolled hypertension,unstable malignant tumor, hepatitis or liver dysfunction, HIV infection. 6, exclusion of unstable mental illness within the previous 6 months; substance addiction or drug-induced mental disorder. 7, unwillingness to sign the informed consent form. 8, pregnant or lactating women; 9. unable to cooperate with the completion of follow-up; 10. Any other diseases or conditions that are not suitable for participation in this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Cognitive activity scale score; | — |
Secondary
| Measure | Time frame |
|---|---|
| Physical examination; | — |
Countries
China
Contacts
Public ContactHou Tingting
Shandong Provincial Hospital of Shandong First Medical University
Outcome results
None listed