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The Impact of Prenatal Volume Adjustment Guided by Inferior Vena Cava Collapse Index Measured by Doppler Ultrasound on Fetal Acidosis: A Prospective Large Cohort Study

The Impact of Prenatal Volume Adjustment Guided by Inferior Vena Cava Collapse Index Measured by Doppler Ultrasound on Fetal Acidosis: A Prospective Large Cohort Study

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500098298
Enrollment
Unknown
Registered
2025-03-05
Start date
2025-04-05
Completion date
Unknown
Last updated
2025-03-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pregnancy and Cesarean Section

Interventions

IVC-CI group:None
Control group:None

Sponsors

Yichang Central People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 45 Years

Inclusion criteria

Inclusion criteria: 1) Age: 18-45 years; 2) ASA classification II-III; 3) Gestational age: 37-42 weeks; 4)The patient or legal representative signs the informed consent form.

Exclusion criteria

Exclusion criteria: 1) Pregnant women with other comorbidities that are not well-controlled, such as hypertension, diabetes, chronic pain, epilepsy, asthma, renal function impairment (BUN and/or Cr > 2 times the normal value), liver function impairment (ALT and/or AST > 1.5 times the normal value), etc.; 2) Pregnant women with special obstetric conditions: placental abruption, placenta previa with bleeding, fetal abnormalities, umbilical cord prolapse, entanglement, twin or multiple pregnancies; 3) Pregnant women who require an emergency cesarean section due to special circumstances, such as fever with acute infection, trauma, etc., but excluding normal obstetric emergencies, such as labor arrest, abnormal fetal heart rate monitoring; 4) Pregnant women allergic to any anesthetic component; 5) Pregnant women who refuse, disagree, or cannot understand the trial protocol; 6) Patients with other conditions that, in the opinion of the researcher, are not suitable for inclusion.

Design outcomes

Primary

MeasureTime frame
Umbilical cord blood pH;

Secondary

MeasureTime frame
Other parameters of umbilical cord blood blood gas analysis;Hemodynamic parameters during surgery, including blood pressure and heart rate;Mother's postoperative recovery score;Infant outcome indicators, including death, admission to a level three neonatal intensive care unit, and the occurrence of respiratory complications, etc.;Apgar score at 1 minute, 5 minutes, and 10 minutes after the delivery of the fetus;

Countries

china

Contacts

Public ContactGong yuan

Yichang Central People's Hospital

gy-yc@163.com+86 139 8674 6821

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026