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Inducing gamma oscillations and the effects of 40Hz sound stimulation on the quality of postoperative recovery after general anesthesia in elderly patients

Inducing gamma oscillations and the effects of 40Hz sound stimulation on the quality of postoperative recovery after general anesthesia in elderly patients

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500098286
Enrollment
Unknown
Registered
2025-03-05
Start date
2024-08-19
Completion date
Unknown
Last updated
2025-03-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Diseases of the elderly

Interventions

study group:40hz acoustic signal stimulation through headphones
control group:only wear headphones with no acoustic signal stimulation

Sponsors

Tongji Hospital, Shanghai
Lead Sponsor

Eligibility

Sex/Gender
All
Age
65 Years to 110 Years

Inclusion criteria

Inclusion criteria: 1. Patients undergoing elective general anesthesia for abdominal surgery, joint replacement surgery, open reduction and internal fixation of fractures, and thoracic non-cardiac surgery are expected to enter PACU for resuscitation. 2. Age >=65 years old 3. Preoperative ASA grade I ~ III 4. Volunteer to participate in the study and sign the informed consent

Exclusion criteria

Exclusion criteria: 1. With serious disease of heart head blood-vessel, severe chronic obstructive emphysema, severe liver or kidney dysfunction; 2. Have a clear diagnosis of mental illness, patients with long-term use of psychotropic drugs; 3. The history of illicit drugs or other drugs abuse; 4. The patient had severe visual or auditory impairment; 5. Those who have participated in drug clinical trials within 30 days; 6. Head facial deformity makes EEG monitoring can not be completed.

Design outcomes

Primary

MeasureTime frame
Postoperative Quality of Recovery Scale;Riker sedation agitation scale;

Secondary

MeasureTime frame
Confusion Assessment Method,CAM;behavioral pain scale,BPS;behavioral pain scale for the non-intubated patient,BPS-NI;numerical rating scale,NRS;Dopamine;Blood gas analysis;

Countries

China

Contacts

Public ContactJianhui Liu

Tongji Hospital, Shanghai

jianhuiliu_1246@163.com+86 136 6145 2939

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026