Chronic insomnia disorder
Conditions
Interventions
Chronic Insomnia disorder:None
Good sleep Control:none
Sponsors
Chengdu Second People's Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: Chronic Insomnia Disorder Patients: 1. Age between 18 and 65 years old, with at least 9 years of education, and right-handed; 2. Meet the diagnostic criteria of the International Classification of Sleep Disorders, Third Edition (ICSD-3); 3. Pittsburgh Sleep Quality Index (PSQI) score > 7; 4. Have not taken any medication within at least 2 weeks prior to entering the study; 5. Voluntarily participate in this study and provide written informed consent. Healthy Controls: 1. Age between 18 and 65 years old, with at least 9 years of education, and right-handed; 2. Pittsburgh Sleep Quality Index (PSQI) score < 5; 3. Have not taken any medication within at least 2 weeks prior to entering the study; 4. Voluntarily participate in this study and provide written informed consent.
Exclusion criteria
Exclusion criteria: Individuals with systemic diseases such as hypertension, diabetes, coronary heart disease, obesity (BMI >= 28); those with severe life-threatening primary diseases involving the cardiovascular, cerebrovascular, liver, kidney, and hematopoietic systems; individuals or their first-degree relatives with a history of mental system diseases or organic neurological disorders; those with insomnia caused by alcohol abuse and/or mental drug abuse and dependence (including sleeping pills); those with severe depression or anxiety symptoms (with a score > 72 on the Self-Rating Depression Scale [SDS] and > 69 on the Self-Rating Anxiety Scale [SAS]); those with severe headaches, migraines, a history of head trauma or surgery; those who are pregnant or planning to become pregnant or breastfeeding; those with contraindications for magnetic resonance scanning such as claustrophobia, implanted metal objects in the body, or metal braces.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Insomnia related scale ; | — |
Secondary
| Measure | Time frame |
|---|---|
| Cognitive function;Brain structural/functional networks;Multi-omics indicators; | — |
Countries
China
Contacts
Public ContactLiang Gong
Chengdu Second People's Hospital
Outcome results
None listed